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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
3-Phenoxybenzoic acid (3-PBA) is the primary urinary metabolite of pyrethroid insecticides, a large family of pesticides found in over 1,500 commercial products for agricultural, residential, and veterinary use.
Key benefits of 3-Phenoxybenzoic Acid (3-PBA) testing
- Pyrethroid insecticide class exposure tracking
- household and agricultural pesticide burden assessment
What is 3-Phenoxybenzoic Acid (3-PBA)?
3-PBA is the primary urinary metabolite of pyrethroid insecticides - a class of synthetic pesticides used in household insect sprays, mosquito control products, treated pet products, and agricultural applications. Measured via LC-MS/MS.
Why is 3-Phenoxybenzoic Acid (3-PBA) important?
Pyrethroids are the most widely used household insecticides globally. Research suggests potential neurotoxic effects of chronic low-level exposure. 3-PBA is one of the most widely used biomarkers for combined exposure to the pyrethroid class, regardless of which specific compound caused exposure.
What insights will I get?
Your 3-PBA level may reflect household insecticide use, treated pet products, conventional produce exposure, or proximity to mosquito control programs. Elevated levels may inform a decision to switch to lower-toxicity pest management alternatives.
