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Mycophenolic Acid

Mycophenolic Acid

Mycophenolic acid is an immunosuppressive fungal metabolite produced by Penicillium species found in water-damaged buildings and certain refrigerated or poorly stored foods.
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Key benefits of Mycophenolic Acid (MPA) testing

  • Mycophenolic acid Penicillium mold exposure tracking
  • grain and fruit contamination monitoring

What is Mycophenolic Acid (MPA)?

Mycophenolic acid is a mycotoxin produced by Penicillium and some Aspergillus species, found in improperly stored grains, some fruits, and cheese. MPA is also the active ingredient in some immunosuppressive medications. Detected in urine via LC-MS/MS.

Why is Mycophenolic Acid (MPA) important?

Dietary MPA may add to any pharmaceutical MPA exposure in members on mycophenolate-based immunosuppressive therapy. For members not on such medications, urinary MPA reflects dietary mycotoxin exposure from contaminated food sources.

What insights will I get?

Your MPA level may reflect dietary exposure from Penicillium-contaminated grains, fruits, or cheese, or pharmaceutical use of mycophenolate-based medications. Discuss any elevated MPA findings with your care team in the context of current medications.

Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.

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