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Aflatoxin M1

Aflatoxin M1

Aflatoxin M1 is formed in the body after ingesting aflatoxin B1, a mycotoxin produced by Aspergillus species that commonly contaminate corn, peanuts, grains, and spices.
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Key benefits of Aflatoxin M1 (AFM1) testing

  • Aflatoxin exposure tracking from contaminated grains and dairy
  • potent hepatotoxin and carcinogen monitoring

What is Aflatoxin M1 (AFM1)?

Aflatoxin M1 is the primary urinary metabolite of Aflatoxin B1, one of the most potent naturally occurring carcinogens. AFM1 is produced when animals consume aflatoxin-contaminated feed and is also excreted in milk - entering the human food chain through dairy products. Measured in urine via LC-MS/MS.

Why is Aflatoxin M1 (AFM1) important?

Aflatoxins are produced by Aspergillus molds on improperly stored crops - particularly corn, peanuts, tree nuts, and some spices. Aflatoxin B1 is classified as a Group 1 human carcinogen (per IARC), with documented hepatic effects at chronic high exposures. AFM1 in urine provides a direct personal measure of recent aflatoxin exposure.

What insights will I get?

Your AFM1 level may reflect recent exposure from aflatoxin-contaminated peanuts, corn, tree nuts, or dairy products sourced from aflatoxin-exposed animals. Purchasing high-quality, properly stored nuts and grains and sourcing from regulated suppliers may reduce exposure. Discuss elevated findings with your care team and review dietary sources.

Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.

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