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Method: GC-MS (Gas Chromatography/Mass Spectrometry) measuring organic acid metabolites in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in mmol/mol creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
2-Hydroxybutyric acid arises along the homocysteine-to-cysteine pathway that supplies glutathione production, sitting at the junction where detoxification and methylation meet.
