Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time. Derived from laboratory results. This score or index is not an FDA-cleared test. It aids clinician-directed assessment and is not a stand-alone diagnosis.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Acetate testing
- Acetate production capacity tracking
- gut acidification and peripheral energy substrate assessment
What is Acetate?
Acetate is the most abundant short-chain fatty acid in the human gut, produced by a broad range of bacteria fermenting dietary fiber. This metric estimates your microbiome's functional acetate production capacity from pathway genes by shotgun metagenomics. Reported in rpkm.
Why is Acetate important?
Acetate is used both locally in the gut and peripherally as an energy substrate by muscle and other tissues. It contributes to gut pH regulation and supports the growth of other beneficial microbes. Acetate-producing capacity is a broad marker of overall fermentative microbiome function.
What insights will I get?
Your acetate production capacity reflects the overall fermentative activity of your gut microbiome. Combined with butyrate and propionate capacity, it provides a picture of total SCFA production potential and the degree to which your microbiome may be supporting both gut health and peripheral metabolic functions.





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