Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Bismuth (Bi) testing
- Bismuth medication and cosmetic exposure tracking
What is Bismuth (Bi)?
Bismuth is a heavy metal used in over-the-counter gastrointestinal medications (bismuth subsalicylate - Pepto-Bismol), some cosmetic pigments, and dental alloys. Urinary bismuth primarily reflects recent medication or cosmetic use. Measured via ICP-MS.
Why is Bismuth (Bi) important?
Regular use of bismuth-containing GI medications can result in detectable urinary bismuth. While bismuth is generally considered low-toxicity at typical therapeutic doses, chronic high-level bismuth exposure has been associated with neurological effects in historical medical use contexts.
What insights will I get?
Your bismuth level most likely reflects use of bismuth-containing GI medications or cosmetics in the days before your test. Elevated levels may prompt a review of bismuth-containing product use frequency.
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