Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Cadmium (Cd) testing
- Cadmium exposure tracking
- tobacco smoke and dietary contamination assessment
- kidney health-relevant metal monitoring
What is Cadmium (Cd)?
Cadmium is a toxic heavy metal that accumulates in the body over decades. Primary exposure sources are tobacco smoke, contaminated food (particularly leafy greens and grains from contaminated soils), and industrial settings. Urinary cadmium reflects cumulative body burden. Measured via ICP-MS.
Why is Cadmium (Cd) important?
Cadmium is classified as a known human carcinogen (IARC Group 1). It accumulates in the kidneys and liver, with the kidney being the primary target organ for chronic toxicity. Because urinary cadmium reflects long-term body burden rather than just recent exposure, it is a particularly informative long-term biomarker.
What insights will I get?
Your urinary cadmium level reflects accumulated body burden. Elevated levels may indicate tobacco smoke history (even secondhand), dietary exposure from contaminated soils, or occupational contact. Cadmium levels typically decline only slowly over years following exposure reduction.
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