Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Diphenyl Phosphate (DPP) testing
- Triphenyl phosphate flame retardant exposure tracking
- electronics and furniture chemical burden assessment
What is Diphenyl Phosphate (DPP)?
DPP is the primary urinary metabolite of triphenyl phosphate (TPhP), an organophosphate flame retardant and plasticizer used in electronics, vinyl flooring, nail polish, and foam furniture. Measured via LC-MS/MS.
Why is Diphenyl Phosphate (DPP) important?
Organophosphate flame retardants replaced brominated compounds in many products following regulatory restrictions. TPhP may act as a hormonal disruptor at low-level exposure. DPP in urine is increasingly recognized as a measure of everyday flame retardant exposure from common consumer products.
What insights will I get?
Your DPP level may reflect contact with electronics, foam furniture, vinyl flooring, or nail polish containing TPhP. Elevated levels may suggest high daily exposure from these product categories. Increased ventilation, choosing non-vinyl flooring materials, or switching nail products may affect future results.





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