Alpha-Lipoic Acid

Discover how Alpha-Lipoic Acid can support your energy levels and antioxidant defense as part of your daily wellness routine.

December 5, 2025
Author
Superpower Science Team
Reviewed by
Julija Rabcuka
PhD Candidate at Oxford University
Creative
Jarvis Wang

Key Facts

  • Alpha-lipoic acid is a naturally occurring compound that functions as an antioxidant in both water and fat-soluble environments throughout your body
  • It supports nerve, eye, metabolic, and liver health by protecting cells from oxidative stress and enhancing mitochondrial energy production
  • ALA recycles other antioxidants like glutathione, vitamins C, and E, amplifying your body's natural defense system

Ingredients

Alpha-lipoic acid, 300 mg per capsule.

Why We Chose This

Oxidative stress accumulates with normal aging and intense physical activity, gradually wearing down cellular function. Alpha-lipoic acid addresses this by working uniquely across all tissue types — something most antioxidants can't do. The 300 mg dose is clinically studied for supporting insulin sensitivity, nerve health, and mitochondrial repair. This formulation is particularly valuable for athletes managing exercise-induced oxidative stress and anyone seeking to optimize cellular energy production and longevity.

Frequently Asked Questions About Alpha-Lipoic Acid

What is the supporting research for the benefits of alpha-lipoic acid?
How do I take alpha-lipoic acid?

Take 1 capsule two to three times daily with meals for optimal absorption and tolerability.

Consistency matters more than timing — your body benefits from regular daily intake rather than sporadic doses.

Can I take alpha-lipoic acid with other supplements or medications?

Alpha-lipoic acid may interact with blood sugar medications, thyroid treatments, and blood thinners — check with your healthcare provider before combining. Most supplements pair safely with ALA, though it's wise to discuss your full regimen with your doctor.

Who might benefit from taking alpha-lipoic acid?

People managing blood sugar challenges, athletes facing oxidative stress from intense training, and those seeking nerve and liver support benefit from alpha-lipoic acid's antioxidant protection. Men interested in fertility support and anyone wanting to optimize cellular energy production may also find it valuable.

How long does it typically take to notice effects of alpha-lipoic acid?

Most people notice improvements in 3 to 5 weeks with oral supplementation, though intravenous administration shows results faster. Individual timelines vary based on dosage, health status, and what you're targeting.