Betaine HCL & Pepsin | Explore Supplements Curated By Superpower

Support your digestive health and nutrient absorption with Betaine HCL & Pepsin to help your body get more from the foods you eat.

December 5, 2025

Author

Superpower Science Team

Reviewed by

Julija Rabcuka

PhD Candidate at Oxford University

Creative

Jarvis Wang

Content

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Key Facts

A combination of betaine hydrochloride and pepsin that supports stomach acid production and protein digestion
Helps optimize the digestive environment, particularly as stomach acid naturally declines with age
Supports nutrient absorption and reduces occasional bloating, gas, and indigestion

Ingredients

Betaine hydrochloride, 1 g; pepsin (porcine), 47 mg.

Why We Chose This

Stomach acid does heavy lifting beyond digestion — it activates pepsin to break down protein, sterilizes food against pathogens, and enables absorption of B12, iron, and minerals like calcium and magnesium. Yet acid production naturally drops with age, and overuse of antacids can suppress it further, leaving you with poor protein digestion and nutrient gaps. Betaine HCl & pepsin directly addresses this by replenishing both the acid environment and the enzyme needed to process protein, helping restore the digestive cascade that supports both comfort and nutrient uptake.

Frequently Asked Questions About Betaine HCL & Pepsin

What is the supporting research for the benefits of betaine HCL & pepsin?

Betaine HCl appears to rapidly reduce gastric pH in studies. (gastric re-acidification study)
It may improve solubility and absorption of pH-sensitive drugs. (clinical overview)
A case report described potential symptom improvement in dumping syndrome. (clinical case report)

How do I take betaine HCL & pepsin?

Take 1–2 capsules with each meal to support stomach acid and protein digestion.

Swallow capsules whole — don't open them, as the powder can irritate your mouth and throat.

Can I take betaine HCL & pepsin with other supplements or medications?

Avoid taking Betaine HCL & Pepsin with H2-blocking drugs and proton pump inhibitors, as these medications block stomach acid production. People taking NSAIDs, cortisone-like drugs, or medications that might cause peptic ulcers should not use this product.

Who might benefit from taking betaine HCL & pepsin?

People with low stomach acid — whether from aging, antacid overuse, or digestive challenges — benefit from this supplement because it restores the acid needed for proper protein breakdown and nutrient absorption. Those experiencing indigestion, bloating, or poor nutrient absorption may find it particularly helpful for supporting digestive function.

How long does it typically take to notice effects of betaine HCL & pepsin?

Effects begin rapidly — typically within 6 minutes of taking the supplement with a meal. The acidifying effect lasts roughly 75 minutes, providing a window for improved protein digestion and nutrient absorption during that time.

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