Pancreatic Enzymes

Digestive Support

Pancreatic Enzymes

Pancreatic Enzymes support healthy digestion by providing lipase, protease and amylase to help break down fats, proteins and carbohydrates. They may help reduce symptoms of pancreatic insufficiency and common digestive complaints like bloating, gas, indigestion and fatty stools while improving nutrient absorption.

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Key Facts

Pancreatic enzymes are digestive proteins that break down fats, proteins, and carbohydrates into absorbable forms
They support nutrient absorption and occasional digestive discomfort by mimicking your body's natural enzyme production
Derived from porcine pancreatic tissue, these enzymes work directly in your digestive tract to enhance meal breakdown

Ingredients

Pancreatin (porcine), hypromellose capsule.

Why We Chose This

Pancreatic enzymes address a real gap: when your pancreas underproduces digestive enzymes — whether from age, stress, or occasional digestive sluggishness — meals don't break down efficiently, leaving you feeling bloated or uncomfortable. Thorne's formulation uses high-quality porcine pancreatin, a clinically recognized enzyme source that mirrors what your body naturally produces. The 1-gram dose provides meaningful lipase, protease, and amylase activity to support fat, protein, and carbohydrate digestion. This straightforward, research-backed approach aligns with our focus on clean, effective supplements that work with your body's existing systems rather than around them.

Other Digestive Support

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FiberMend is a fast-acting, natural fiber supplement designed to restore gentle bowel regularity and support overall digestive health. It may help relieve constipation and bloating, promote healthy stool formation, and support metabolic health (e.g., blood sugar and cholesterol) when used with a balanced diet and lifestyle.

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Frequently Asked Questions About Pancreatic Enzymes

What is the supporting research for the benefits of pancreatic enzymes?

Pancreatic enzymes are associated with improved fat absorption and reduced symptoms. (classical PERT trial)
Modern enzyme preparations are associated with improved stool frequency and pain reduction. (PERT clinical study)
Appropriate dosing of pancreatic enzymes appears critical for symptom control. (evidence review)

How do I take pancreatic enzymes?

Take 1-2 capsules with each meal or snack, swallowing with enough liquid to ensure complete ingestion.

Spread your dose throughout the meal rather than taking all capsules at once for optimal enzyme distribution.

Can I take pancreatic enzymes with other supplements or medications?

Pancreatic enzymes can generally be taken with most medications and supplements, though certain interactions warrant attention. Antacids and magnesium supplements may reduce enzyme effectiveness, so spacing doses by at least one hour helps maintain optimal digestion support.

Who might benefit from taking pancreatic enzymes?

People with pancreatic enzyme insufficiency — from conditions like cystic fibrosis, chronic pancreatitis, or pancreatic cancer — benefit from pancreatic enzymes to improve fat, protein, and carbohydrate digestion. Those experiencing occasional indigestion or digestive discomfort may also find support with these supplements.

How long does it typically take to notice effects of pancreatic enzymes?

You should notice improvements within a single meal if your dose is in the right ballpark, with reduced bloating, gas, and diarrhea appearing within days. Longer-term benefits like weight stabilization and corrected nutritional deficiencies typically take weeks to months.

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